Clinical trial for COVID-19 vaccine opening in Gulfport

The National Institute of Allergy and Infectious Diseases is sponsoring a clinical trial for COVID-19 patients in Gulfport.

The ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial is open for enrollment. Its primary goal is to determine whether investigational agents may effectively and safely treat COVID-19 among adults who have it but aren’t sick enough to be hospitalized.

Clinical trials are vital to discovering medical treatments and they only work when enough people volunteer. Individuals in the Mississippi Gulf Coast area who have been diagnosed with COVID-19 in the past week and are not in the hospital can make a huge contribution by participating in the ACTIV-2 study.

The ACTIV-2 clinical trial has been designed to identify treatments with the potential to alter the current pandemic landscape. The National Institute of Allergy and Infectious Diseases is part of the National Institutes of Health.

According to a press release, COVID-19 treatments that can speed recovery and prevent people from progressing to advance disease, requiring hospitalization, and transmitting SARS-CoV-2 are desperately needed.

At least half of those enrolled in ACTIV-2 will have risk factors for progression to more severe disease, such as age over 55 or underlying conditions like chronic lung, kidney, or liver disease; obesity; hypertension; cardiovascular disease; diabetes; or moderate to severe asthma.

In addition, the trial will aim to enroll Black, Indigenous, Hispanic, and other communities of color who are disproportionately acquiring, being hospitalized with, and dying from COVID-19. The ACTIV-2 trial is committed to enrolling individuals from these communities, and working closely with community partners to get information about the trial to those who have been under-represented in clinical research.

The study website,, lists where the study is enrolling nationwide and connects to a Contact Center where operators are available 24/7 to link those who seem eligible for the study to nearby study centers. Callers can also directly call the Contact Center at 877-345-8813

Dr. Paul Matherne, MD is a family medicine specialist in Biloxi, MS and has over 42 years of experience in the medical field. He graduated from LSU School of Medicine, Shreveport medical school in 1978. He is affiliated with medical facilities such as Garden Park Medical Center and Memorial Hospital at Gulfport. Matherne has multiple years of experience in clinical trials including maternal, pediatric, and adult vaccine trials.

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