While most of the favorites are well established as the season pushes past the midway point, the week-to-week shuffling among the nation's elite is sure to continue down the stretch, even if the very top of this list remains unchanged this week.
Breakin' up is hard to do, at least according to Neil Sedaka.
Peyton Manning's latest feat might be his most impressive.
Baltimore Ravens long snapper Morgan Cox suffered a torn right anterior cruciate ligament during Sunday's 29-7 win over Atlanta and is likely done for the season.
The SEC has long been considered the top conference in college football and the latest Associated Press poll is further proof, as four of the top five teams are from the powerful league.
Buffalo Bills running backs Fred Jackson and C.J. Spiller both exited Sunday's 17-16 win over the Minnesota Vikings and didn't return.
Cincinnati Bengals wide receiver A.J. Green is inactive for Sunday's game against Indianapolis because of a lingering toe injury.
Carolina Panthers rookie wide receiver Kelvin Benjamin is active for Sunday's game against Green Bay after recovering from a concussion.
Charlie Whitehurst will start at quarterback in place of Jake Locker for the Tennessee Titans in Sunday's game against the Washington Redskins.
Detroit Lions wide receiver Calvin Johnson is inactive for Sunday's game against New Orleans because of a high ankle sprain.